New paper: defining dwarfing rate of an extinct dwarf elephant!

New paper: ancient DNA from museum wet collection specimens!

New paper on defensive venom in cobras!

New paper on Middle Pleistocene cave bear!

Welcome to Axel Barlow’s

Pleistocene Genomics Lab

We use palaeogenomics to study the evolution and ecology of Pleistocene animals that lived tens of thousands of years ago!

Latest News

New paper on leopard genomes!

We sequenced leopard genomes from all over their distribution, and found a striking genomic distinction between African and Asian leopards! Check out the results, published in Current Biology: Paijmans JLA, Barlow A, Becker MS, Cahill JA, Fickel J, Förster DWG, Gries K, Hartmann S, Havmøller RW, Henneberger K, Kern C, Kitchener AC, Lorenzen ED, Mayer …

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by Johanna Paijmans 22nd Apr 202122nd Apr 2021

New paper on museum linsang DNA!

We were part of an international team recovering DNA from museum samples of Asian linsangs. Check out the results in the paper, published in PLoS ONE! Paijmans JLA, Barlow A, Henneberger K, Fickel J, Hofreiter M, Foerster DWG (2020) Ancestral mitogenome capture of the Southeast Asian banded linsang. PLoS ONE. 15(6): e0234385. https://doi.org/10.1371/journal.pone.0234385

by Axel Barlow 9th Jul 202022nd Apr 2021

New paper on DNA sequences from museum frog specimens!

We were part of an international team recovering mitochondrial sequences from South American frog museum specimens. This data helped resolve long-standing questions on the taxonomy of the group! Check out: Lyra ML, Lourenço ACC, Pinheiro PDP, Pezzuti TL, Baêta D, Barlow A, Hofreiter M, Pombal José PJR, Haddad CFB, Faivovich J (2020) High-throughput DNA sequencing …

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by Axel Barlow 18th Jun 202022nd Apr 2021

New paper on cave bear diet out!!!

We were on the team finally solving the puzzle of the unusual isotopic signals in Romanian cave bears: they were herbivorous after all! New paper published in Scientific Reports: Naito YI, Meleg IN, Robu M, Vlaicu M, Drucker DG, Wißing C, Hofreiter M, Barlow A, Bocherens H (2020) Heavy reliance on plants for Romanian cave …

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by Axel Barlow 21st Apr 2020

New paper on cave hyena palaeogenomes, published in Science Advances!

We were part of the team presenting the first palaeogenomes from extinct Pleistocene cave hyenas, and uncovering their relationship to modern hyenas. Check ou tthe new paper in the current issue of Science Advances! https://advances.sciencemag.org/content/6/11/eaay0456 And a write up on physorg: https://phys.org/news/2020-03-prehistoric-hyenas-humans-migration-patterns.html

by Axel Barlow 17th Mar 2020

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Research Themes

Palaeogenomics

We collect genomic data from ancient subfossil bones to study the evolution and ecology of Pleistocene animals. Find out more

Laboratory methods

Our work also involves the development and optimisation of new laboratory methods for recovering palaeogenomic data. Find out more

Bioinformatics

We also develop new computational and statistical methods for the analysis of palaeogenomic data. Find out more

Museum samples

We are also interested in the genomic analysis of historical museum specimens as a way of sampling endangered and recently extinct animals. Find out more

Phylogenetics

We also generate datasets for phylogenetic analysis and molecular dating. Find out more

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